Winning the fight against arthritis. That would be a good thing.

But knowing about it is pretty critical to ridding yourself of arthritis.

Obesity and progression of RA seems to go hand in hand. Obese patients seem to have higher level of disease activity compared to those with normal weight according to the study. Consequently, they also need more aggressive treatment to control the disease symptoms compared to other non-obese patients.

For the study, researchers collected data on 3534 patients from the Meteor Foundation International RA database. Of these, 1553 showed early RA, which refers to the disease that has developed within 12 months and the remaining 1981 had established RA.

The patients were then classified based on their body mass index. They were divided into 5 categories – underweight, normal, overweight, obese I and obese II. The analysis of the data revealed that both underweight and obese II patients were twice as likely as normal weight patients to have higher levels of disability.

Obese I patients were 1.5 times as likely as normal weight patients to develop functional incapability. These observations held true for both early an established RA.

Higher levels of inflammation and health impairment were the factors that were assessed for progression in disease activity. For instance, the researchers have suggested that adipokines, chemical components in fat cells of obese patients, can trigger systemic inflammation and also cause joint destruction.

Losing weight is probably one of the most important steps for obese patients to control the symptoms of RA.

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