This apple blocks gout flares

A natural plant compound in a common type of apple can block gout from flaring up, in similar ways as drugs do.

…without the side effects.

This is according to a new study published in Food Bioscience.

Here’s the problem.

Seafood, red meat, alcohol, and some other foods are rich in a compound called purine.

So, when you eat them, your body breaks down these purines.

The enzyme responsible for this breakdown is called xanthine oxidase (XO).

XO converts purine to hypoxanthine, hypoxanthine to xanthine, and xanthine to uric acid.

Brilliant — job done.

Except, there’s a major problem.

Gout occurs when uric acid builds up in the bloodstream and forms crystals in the joints, causing inflammation and intense pain.

When XO is overactive, it leads to excess uric acid, contributing to gout.

Traditionally, drugs like allopurinol inhibit XO to reduce uric acid production.

But they can cause side effects such as liver and kidney problems.

This has led researchers to investigate natural compounds that could inhibit XO without harmful side effects.

One such compound is phloretin, a plant-based flavonoid found in green apples that has been shown to inhibit XO effectively.

However, the presence of other dietary factors, such as unsaturated fatty acids, may enhance or interfere with this effect.

The authors of this study examined the impact of three unsaturated fatty acids on the interaction between phloretin and XO:

• Oleic acid

• Linoleic acid

• Alpha-linolenic acid

They conducted their experiments in the laboratory.

Here’s a breakdown of how these fatty acids contributed to the process:

• All three fatty acids boosted phloretin’s ability to block XO and thereby reduce uric acid production.

• Alpha-linolenic acid worked best, followed by oleic acid, then linoleic acid.

• The fatty acids increased phloretin’s ability to bind to XO. This improved the strength and stability of the inhibitor-enzyme complex, making it more effective at blocking XO’s activity.

• The fatty acids disrupted the hydrogen bond network of XO, leading to a more disordered structure of the enzyme. This disruption made it easier for phloretin to bind to XO and inhibit its activity.

This study shows that the right food can directly block gout flares.

Step further: You can heal your gout for good with the right food and a few other lifestyle adjustments.

Thousands of readers are living proof of this.

Here are the exact steps they took to heal their gout naturally…