If you have been diagnosed with gout, you’ve probably been advised to cut down on uric acid.
That’s just half the story, according to a new study in Frontiers in Microbiology.
The only way to cure gout permanently is by loading up on specific bacteria found in many common foods.
Recent studies suggest that people with gout have different gut bacteria than other people. Based on this information, this study’s researchers wanted to find out two things.
First, they wanted to find out whether Ligilactobacillus salivarius could break down substances related to purines (chemicals in the body that can lead to high uric acid levels).
Second, they wanted to find out whether giving a chosen strain of this type of bacteria to people with a history of high uric acid levels could be beneficial.
They performed this study in two phases, the first in the laboratory and the second on a sample of human participants.
In the first phase, they identified and measured several purine-related substances using a method called high-performance liquid chromatography. They then tested how a selection of L. salivarius strains affected these substances using whole bacteria cells and their components.
In this phase of the study, they discovered that the Ligilactobacillus salivarius strain CECT 30632 was the most effective at breaking down purine substances and rendering them harmless. It broke down 100% of inosine, 100% of guanosine, and 50% of uric acid.
In the second phase, they tested this strain on human subjects by recruiting 30 people who had high uric acid levels and had suffered repeated gout attacks.
For 6 months, half of the patients took Ligilactobacillus salivarius strain CECT 30632 daily, and the other half took a standard gout medication called allopurinol.
The researchers monitored the patients’ health progress, medication intake, and changes in various blood markers.
The Ligilactobacillus salivarius CECT 30632 succeeded beyond their expectations. In comparison with those who took the standard gout medication, those who took this bacteria strain showed the following improvements:
1. A significant reduction in the number of gout episodes.
2. A reduction in the use of gout-related drugs.
3. An improvement in some blood parameters related to oxidative stress, liver damage, and metabolic syndrome.
These findings mean that Ligilactobacillus salivarius CECT 30632 is a better gout treatment than the standard gout medication on the market.
Probiotic supplements that contain Ligilactobacillus salivarius are commonly available, but ones in which this specific strain dominates are, unfortunately, much harder to find.
The Ligilactobacillus salivarius family is abundant in yogurt, garlic, bananas, and asparagus.
The most important thing about this study is that it proves what I have been teaching for over a decade: healing gout is not about cutting down on uric acid; it’s about breeding the right gut bacteria. Ligilactobacillus salivarius is just one of many types of gut bacteria that consume uric acid.