A professor and her students from the University of Delaware were studying genetic contributions to Alzheimer’s disease when they accidentally stumbled onto something shocking.
According to their new study, published in Cell Reports, one common vitamin that is found in all pharmacies can block the onset of Alzheimer’s.
As strange as it may seem, medical scientists do a lot of their research on worms. Human genetics, diets, and behaviors are so complex that it can be difficult to work out whether and how one factor interacts with other factors to produce a disease.
Worms, on the other hand, are cellularly simple: they mostly have the same genes and their diets can be controlled in the lab. So, they’re a great starting point for the study of diseases.
While performing their studies on the genetic factors responsible for Alzheimer’s, and after injecting the worms with amyloid beta to cause Alzheimer’s, these researchers noticed that some of their research worms were completely paralyzed, while others could still wiggle.
Then, they discovered that while all the worms were fed on E. coli bacteria, one of the strains contained more vitamin B12 than the other.
Alzheimer’s causes paralysis in worms, but the group that was fed the higher levels of vitamin B12 could still move.
They immediately set their genetic research aside for a while and focused their attention on this vitamin and its effects on Alzheimer’s.
They deliberately fed one group of worms a diet high in Vitamin B12 and starved the other group of this important vitamin.
Just as they expected, the worms who got extra B12 seemed to have a shield against Alzheimer’s, especially those who were deficient in Vitamin B12 before.
Does this apply to humans too?
A lot of research still must be performed to answer this question, but since vitamin deficiencies are common in elderly people, who usually start to eat less as they age, it definitely warrants further study.
In the meantime, it definitely doesn’t hurt to supplement with Vitamin B12, as most people don’t get enough of it.