Scientists have been debating for decades how significant a role lifestyle changes play in type 2 diabetes versus genetic predisposition.
To try to put this matter to a rest, new study recently searched through the entire genetic code of 2,657 diabetics and nondiabetics and the protein producing genes of 12,940 people. With less complete genetic information, they also predicted the diabetes risk of 111,000 further people.
What they discovered was something quite amazing. And it points to a solution that resembles yesterday’s science fiction.
It was indeed common genetic variations that significantly contribute to type 2 diabetes. There are, however, many such variations and each contributes only a tiny amount of risk.
Why is this important?
Four years ago, professors at Berkeley University of California, invented a now widely used and apparently safe method to edit human genes.
Doctors are now able to delete defective DNA strands from genes and insert strands that lack harmful mutations.
Therefore, if scientists can agree on the genetic mutations that make people vulnerable to type 2 diabetes, they will soon be in a position to delete them and replace them with healthy DNA.
It’s important to understand, however, that new type 2 diabetes cases are doubling every few years now.
Our genes are not changing a lot but our lifestyles are.
This proves that it’s indeed our lifestyles that are the main cause of type 2 diabetes, even if it may be our genes that make us vulnerable to the impact of those lifestyles.
DNA technology is also very new. It’s amazing to help with clear genetic diseases that may leave people bedridden or blind for their whole lives.
But when scientists are playing with several hundred different genes that may contribute to type 2 Diabetes, there is a lot of room for things to go wrong. Maybe “fixing” some of these genes will make you more vulnerable to other unknown diseases.