If you search for the symptoms of hypothyroidism online, you are likely to find fatigue, weight gain, muscle aches and weakness, depression, sensitivity to cold, constipation, and so forth.
But a study in the journal Neuropsychiatric Disease and Treatment reveals a newly discovered symptom. One that is more terrifying than all the others put together.
And using medications will not help with this one.
Researchers from the University of Gondar in Ethiopia wanted to know what percentage of hypothyroidism sufferers have difficulty with decision-making, concentration, memory, and other cognitive skills.
In addition, they wanted to establish which other factors contributed to cognitive impairment in this population.
They recruited their participants from Amhara Regional State medical centers where they had been officially diagnosed with hypothyroidism. They were all receiving thyroid hormone (levothyroxine) replacement therapy.
Patients with epilepsy or any other seizure disorder, stroke, a hearing problem, and any psychiatric disorder were excluded. They eventually had 216 subjects with an average age of 42, the oldest being 72 and the youngest 18.
They took their subjects’ thyroid-stimulating hormone levels and thyroid hormone levels from their hospital charts. They obtained their demographic and other health information from a pre-study interview or questionnaire.
They then gave them the standard Standardized Mini-Mental State Examination (SMMSE) questionnaire that tested various cognitive skills including memory, language, attention, calculation, orientation, and registration.
Overall, 27.3 percent of their subjects had low enough scores on the SMMSE to qualify as cognitively impaired.
This was higher for women (31.6 percent), for people from rural areas (30.3 percent), and for people with only grade eight and lower education (30 percent).
Old age, a long duration of hypothyroidism, and high levels of thyroid-stimulating hormone all contributed to the cognitive impairment, while other demographic factors like marital status and monthly income did not.
When they compared their study with previous investigations of the same question, they found that their results were relatively similar.
A previous study in India found cognitive impairment in 32.2 percent of subjects, while a study in Los Angeles discovered it in 28 percent of theirs. The slightly lower rate in Ethiopia may have been because three language questions had to be excluded from the study for subjects who could not read or write.
As mentioned earlier, the subjects in this study were all receiving levothyroxine replacement drugs, which is certainly not a ringing endorsement for them with so many patients still struggling to concentrate, calculate, recall, and understand.