Nail fungus is stubborn. Nothing works long-term.
That’s until now.
A common spice combined with a simple light can kill over 90% of nail fungus.
The proof: a new study published in Social Science Research Network.
The study’s authors wanted to investigate the effectiveness of curcumin combined with blue light photodynamic therapy in combating nail fungus.
This is how the theory of this therapy works.
Photodynamic therapy uses light-sensitive compounds, known as photosensitizers, which are activated by specific wavelengths of light. When exposed to this light, the photosensitizers produce reactive oxygen species, which damage the cell walls of the targeted fungi, leading to their destruction.
For their study, the researchers decided to use curcumin as a photosensitizer. Curcumin, the active compound in turmeric, has excellent anti-inflammatory and antioxidant properties. However, in its natural form it isn’t strong enough to work with photodynamic therapy.
To enhance its effectiveness, they developed two concentrated versions, which they called compounds 9 and 10. Previous studies had already shown evidence of antibacterial activity, but they wanted to see whether it would work equally well against Trichophyton rubrum, a common culprit behind nail fungus.
In this study, compounds 9 and 10 were applied to the fungal-infected area, and blue light irradiation was use to activate the compounds. The treatment lasted 30 minutes, after which the inhibition rates of the fungus were measured.
The results were impressive.
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1. Compound 9 destroyed 90.35% of the fungi, while compound 10 wiped out 90.88%. This shows a significant fungicidal effect.
2. Using scanning electron microscopy technology to visualize the effects on the fungal cells, they could see major damage inflicted on the Trichophyton rubrum cells, further confirming the success of the treatment.
3. The combination of curcumin and blue light photodynamic therapy did its job in a way that minimized harm to surrounding healthy tissues.
This effectiveness and safety make this therapy an attractive option for treating stubborn nail fungus, especially in cases where all else has failed.
While this type of photodynamic therapy is promising, it is not yet available as a treatment. Doing it at home won’t work, as consumers cannot obtain the specific curcumin compounds the researchers used in the study.